SNPs in the PAM region leading to guanine (G) to Y change, where Y represents cysteine (C) or taurine (T), were preferred, as these changes exhibited the best discrimination of scFv-DNMT3A/3L ...

The tools needed to pinpoint the problematic variants have been lacking. To fill this gap, Farh and his team have developed a deep neural network— PromoterAI —that accurately identifies promoter ...

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.