In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

When the gene editing tool CRISPR-Cas9 rocketed to fame more than a decade ago ... “CRISPR gene editing is a transformative technology for addressing genetic diseases, but delivery constraints have ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers ... Scientists employ these knockout or knock-in cells for numerous applications including analyzing gene function, ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

2024 — Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the ...

By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...