《Cell Death & Differentiation》:ATOH8 confers the vulnerability of tumor cells to ferroptosis by repressing SCD expression ...
Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.
Erastin and RSL3, ferroptosis inducers, reduce pro-inflammatory cytokines in macrophages. In tumor microenvironments, substances like 8-OHG drive macrophage polarization towards the ...
Researchers from Soochow University and affiliated organizations presented data from a study that aimed to investigate the role of cyclic GMP-AMP synthase (cGAS) in tumorigenesis and tumor progression ...