such as pneumonia and acute respiratory distress syndrome (ARDS). A recent Nature Communications study identifies ferroptosis as a major cell death mechanism underlying COVID-19 lung disease.

These findings open up new avenues for the development of targeted therapies aimed at regulating histone modifications and ferroptosis in the treatment of sepsis-related ARDS.

H3K14la drives endothelial dysfunction in sepsis-induced ARDS by promoting SLC40A1/transferrin-mediated ferroptosis Sichuan International Medical Exchange and Promotion Association Journal MedComm DOI ...