Unlike full-length mAbs, however, fragments (unless designed otherwise) fail to induce effector functions that require an Fc domain, such as antibody-dependent cell-mediated cytotoxicity or ...

It performs an enzymatic modification method of IgG Fc glycans to perform conjugation. AGLink requires no prior engineering of the amino acid sequence, resulting in stable antibody conjugates ...

For outsourcing therapeutic antibody discovery ... fully human Fab and upper hinge regions and mouse middle hinge and Fc regions. Optimized constant domains enable the rapid generation and ...

Seismic Therapeutic, Inc., the machine learning immunology company, today announced the dosing of the first healthy subject ...

Proteintech has designed recombinant antibodies featuring the company's FcZero backbone, engineered to silence the Fc domain ...

Complementing its antibody offerings, BosterBio provides a range of ELISA kits designed for quantitative detection of ...

However, the subsequent complement activation is mediated by the Fc tail. The two antibody clones mediating synergy were derived from the same donor, thus highlighting the possibility that these ...