Unlike full-length mAbs, however, fragments (unless designed otherwise) fail to induce effector functions that require an Fc domain, such as antibody-dependent cell-mediated cytotoxicity or ...

It performs an enzymatic modification method of IgG Fc glycans to perform conjugation. AGLink requires no prior engineering of the amino acid sequence, resulting in stable antibody conjugates ...

Seismic Therapeutic, Inc., the machine learning immunology company, today announced the dosing of the first healthy subject ...

Proteintech has designed recombinant antibodies featuring the company's FcZero backbone, engineered to silence the Fc domain ...

Additional Phase 2 data for vilastobart,a tumor-activated, Fc-enhanced anti-CTLA-4, in combination with atezolizumab in patients with MSS CRC ...

Recombinant Monoclonal Antibodies: It is made up of identical antibody chains that target the ... These fragments have the antigen-binding regions sans the Fc region, thus reducing their size ...

Complementing its antibody offerings, BosterBio provides a range of ELISA kits designed for quantitative detection of ...

For outsourcing therapeutic antibody discovery ... fully human Fab and upper hinge regions and mouse middle hinge and Fc regions. Optimized constant domains enable the rapid generation and ...