How did eukaryotic organisms become so much more complex than prokaryotic ones, without a whole lot more genes? The answer lies in transcription factors. Experiments have shown that TFs can bind ...

Transcription Factors and Human Disease provides an up ... entitled "Transcriptional Regulation," summarizes our basic understanding of eukaryotic transcription. Chapters 1 and 2 describe promoter ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...