Peter Shen, a postdoctoral researcher in Frost’s lab, isolated RQCs from yeast cells and used cryo-electron microscopy to develop three-dimensional images of their interactions with large ribosomal ...

Recently, using cryo-electron microscopy (cryo-EM) and single-particle three-dimensional reconstruction techniques, the binding position of EF-G on the naked ribosome (that is, devoid of mRNA and ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins.

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...

LMU structural biologist Roland Beckmann, in collaboration with researchers at the Max Planck Institute for Biochemistry and the Institut Pasteur (Paris), has now shown that there is a direct ...

View Full Profile. Learn about our Editorial Policies. In 1974, Palade himself took the stage to deliver his own Nobel lecture. The foundation for much of his work was electron microscopy (EM), which ...

The 3D electron microscopy imaging is available using Serial Block Face (SB-EM) and Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) or Electron Tomography (ET) Electron tomography is TEM based ...

Zhang Xinzheng at the Institute of Biophysics, Chinese Academy of Sciences, utilized cryo-electron microscopy (cryo-EM ... eEF3) to the ribosome as well as their dissociation from it.

It is a beautiful piece of work. It provides a serious piece of heft to the hypothesis that specialized ribosomes not only exist but have important functional consequences in cellular processes.

Ribosomes turn upside-down in hungry cells ... Medicine explored it in greater detail using single-particle cryo-electron ...