Dylan McDermott and his rescue dog Otis star in a new PETA pet adoption campaign, and PEOPLE has an exclusive first look at the project's adorable video PSA.

The actor recently sat down with ET for a retrospective on his 40-year career. ET was with Dylan McDermott as he looked back on his nearly four-decade career. In ET's exclusive first look ...

Dylan McDermott is spreading ... needy pet gets "a Hollywood ending." PEOPLE has an exclusive first look at the campaign, which features a video of McDermott, 63, and Otis howling together.