The ability to analyze gene expression at the single-cell level—known as single-cell RNA sequencing (scRNA-seq)—has ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

Gene expression analysis plays a critical role in candidate preclinical safety and toxicity screenings as well as in monitoring therapeutic efficacy and off-target effects to ensure biologics are ...

To enhance productivity in research laboratories conducting genomic studies, automation techniques along with rapid workflows are encouraged. Here, we discuss gene expression analysis by ...

“Hormones and DNA are two powerful factors that can push a gene into being switch-like,” Aqil says. “Typically, lots of small ...

Gene expression analysis using qPCR quantification of RNA transcripts expressed by cells or viruses plays an important role in the discovery and development of novel biotherapeutics. While widely used ...

Gene expression in the human brain: cell types become more specialized, not just more numerous Date: January 2, 2025 Source: University of California - Santa Barbara ...

The team’s in-depth genetic analysis of individual cells revealed that different cell types in the fruit fly body age differently, with each cell type following a process involving cell type ...

Researchers from Skoltech, Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, and Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences have studied ...