More information: Kim L. de Luca et al, Genome-wide profiling of DNA repair proteins in single cells, Nature Communications (2024). DOI: 10.1038/s41467-024-54159-4 Provided by Hubrecht Institute ...

A 'DNA Repair Café' The findings also revealed that DNA can be repaired by cooperation between repair proteins. These proteins organize themselves into "hubs," where multiple damaged DNA regions ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...

Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...

DNA mismatch repair enzymes solve this problem by making ... They also identified some signs of inflammation in the cerebrospinal fluid, proteins that might be used as biomarkers for studies ...

The study, published in Nucleic Acids Research, focused on benzo (a)pyrene, a toxic chemical in cigarette smoke, which binds to DNA when processed by the body, and disrupts its normal function and ...

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

the Berkeley Lab researchers employed a bevy of innovative techniques to measure the DNA repair capacity, repair protein expression profiles, and double-strand break levels across brain regions in ...

Despite their genius, DNA-nanoparticle motors don't have the speed of their biological counterparts, the motor protein, which is where the issue lies. This is where researchers come in to analyze ...

People genetically susceptible to Huntington’s disease often see their movement, mood, and cognition decline slowly over time. The cause is related to expansion of repeating DNA units, in which ...