DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, revealing the molecular processes responsible for a range of cancers.

They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But as they age, they accumulate more and more DNA damage. Until now, it has ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

DNA damage and repair refers to the creation ... involved include the modulation of chromatin state, condensates of repair proteins and cytoskeleton reorganization. The reshaping of the nucleus ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers ...

The egg cell’s ability to repair damage in its DNA is crucial to ensure that it remains functional for a long time and does not die. To this end, egg cells have developed a complex repair machinery ...

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer. But ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide ...

These studies have consistently highlighted the role of DNA repair in influencing the age of onset and disease progression. Among the DNA repair genes identified, MSH3 has emerged as a ...

Egg cells need stamina: They are formed in a woman’s body before birth and have to be on standby for decades to possibly be fertilized one day. But as they age, they accumulate more and more DNA ...