More information: Kim L. de Luca et al, Genome-wide profiling of DNA repair proteins in single cells, Nature Communications (2024). DOI: 10.1038/s41467-024-54159-4 Provided by Hubrecht Institute ...

A 'DNA Repair Café' The findings also revealed that DNA can be repaired by cooperation between repair proteins. These proteins organize themselves into "hubs," where multiple damaged DNA regions ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...

DNA mismatch repair enzymes solve this problem by making ... They also identified some signs of inflammation in the cerebrospinal fluid, proteins that might be used as biomarkers for studies ...

The study, published in Nucleic Acids Research, focused on benzo (a)pyrene, a toxic chemical in cigarette smoke, which binds to DNA when processed by the body, and disrupts its normal function and ...

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

Despite their genius, DNA-nanoparticle motors don't have the speed of their biological counterparts, the motor protein, which is where the issue lies. This is where researchers come in to analyze ...

and Lausanne reveals that the protein machines that shape our DNA can switch directions. The new finding is published in Cell in an article titled, “SMC motor proteins extrude DNA asymmetrically ...

People genetically susceptible to Huntington’s disease often see their movement, mood, and cognition decline slowly over time. The cause is related to expansion of repeating DNA units, in which ...