Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

How do DNA repair mechanisms detect and repair damaged DNA, and what happens when they fail? Defects in DNA repair underlie a number of human genetic diseases that affect a wide variety of body ...