为解决分析 DNA 损伤受细胞组成和损伤随机性干扰的问题，研究人员开发 Paired-Damage-seq，发现损伤与表观遗传变化有关，可预测疾病风险。 在多细胞生物中，基因组完整性的维持对分子程序至关重要。在整个生命过程中，各种内源性和环境因素持续威胁基因组 ...

为探究基因组 DNA 在有丝分裂时如何折叠成杆状染色体，欧洲分子生物学实验室研究人员开展相关研究，发现其通过凝缩蛋白（condensin）挤出重叠环及自排斥形成，为理解遗传信息传递提供依据。 在细胞分裂的微观世界里，遗传信息的准确传递至关重要 ...

By tagging each DNA or RNA molecule and allowing neighboring tags to interact, the technique constructs a molecular network that encodes their relative positions, creating a spatial map of genetic ...

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer. A new process ...

Rex Heuermann's attorneys are asking for more time as they challenge something called nuclear DNA testing, which has never been used in a New York court of law. The judge has set what's called a ...

DNA-testing company 23andMe and its co-founder, Anne Wojcicki, aimed to revolutionize healthcare, bringing genetic tests into homes with just a tube of spit. WSJ takes a look at factors that ...

The most obvious use for genetic data is discovering one’s health predispositions; 23andMe offers a subscription that shows whether a person’s DNA is associated with a likelihood for certain ...

Spit in a tube and, for about $100, discover secrets held by your DNA. That was the promise of 23andMe, a direct-to-consumer genetic-testing company. It proved popular—more than 15m customers ...