The atomic structure of hemoglobin, determined by Max Perutz and colleagues 4, showed that this residue position is located on the surface of the protein. The mutation makes sickle cell hemoglobin ...
Makio Murayama, a Japanese-American biochemist who was turned away from the Manhattan Project due to his heritage, rose to prominence for his work uncovering the link between the structure of ...
The expression of fetal hemoglobin has the potential to normalize hemoglobin composition and the red blood cell counts in patients with transfusion-dependent beta-thalassemia, eventually making them ...