To avoid becoming a commodities industry, combinatorial chemistry companies are broadening their technology base. Since Nature Biotechnology published the first-ever map of the combinatorial ...

In the early 1990s, two complementary technologies — combinatorial chemistry and high-throughput screening (HTS) — were widely seen as having great potential to revolutionize drug discovery.

Dynamic combinatorial chemistry (DCC) involves the creation of a dynamic mixture of compounds carried out under reversible equilibrating conditions. This thermodynamic adaptive chemistry relies on and ...