If you're studying genetics, molecular biology or a related field, odds are good that you will need to learn how to read a codon chart (aka codon table) to better understand the genetic code. This ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Pelc and Welton have recently proposed1 a stereo-chemical relationship between protein amino-acids and the codon triplet of nucleotides. I wish to propose a rather different possible relationship ...

Recently, researchers aiming to add completely new amino acids to a protein have created strategies to reassign a codon. For ...

Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...

Recently, researchers aiming to add completely new amino acids to a protein have created strategies to reassign a codon. For instance, the UAU codon could be linked to a new amino acid by changing ...

“The assignment of the genetic code has some inherent malleability, which one can change to assign existing codons to new amino acids,” said Badran. His team leveraged this by using a plug-and-play ...

Now, scientists at Scripps Research have designed a new paradigm for easily adding non-canonical amino acids to proteins. Their approach, described in Nature Biotechnologyon September 11, 2024 ...