provides valuable insights into the catalytic and noncatalytic functions of the histone methyltransferase SETD2, a protein responsible for histone H3 lysine 36 trimethylation (H3K36me3 ...

Argonaute proteins contain four conserved domains: the N-terminal, PAZ (which is responsible for small RNA binding), Mid and PIWI (which confers catalytic activities) domains. Argonaute proteins ...

Figure 1: Bovine adrenocortical cells were established in culture and transfected with SV40 large T-antigen and the catalytic protein component of telomerase (hTERT). Slowing the rate of telomere ...

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.

The cause, they find, may be natural proteins of the immune system that normally target viruses by damaging their DNA. The proteins are called Apolipoprotein B mRNA editing catalytic proteins, or ...

The proteins are called Apolipoprotein B mRNA editing catalytic proteins, or APOBECs. APOBECs are part of a first response team of proteins used to fight off viral infection until the adaptive ...

Researchers from Zhejiang University and HKUST (Guangzhou) have introduced ProtET, an innovative AI-powered multi-modal protein editing model published in Health Data Science. ProtET leverages ...

The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the overall structure of the ribosome. One of the most remarkable features of rRNA is its catalytic activity ...

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Both deubiquitinases have an S2 catalytic domain in addition to the usual S1 sites, which enhances their ability to target longer chains. Finally, researchers looked for ubiquitinated proteins ...