This disrupts the translation initiation complex and provides degradative enzymes with access to the 5′ cap and remaining RNA body. The intimate relationship between mRNA decay and translation ...

The Ribosome Quality Control Complex (RQC) recognizes and destroys incomplete proteins that protrude from large ribosomal subunits that become detached from the rest of the ribosome when protein ...

With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The researchers discovered that ribosomes help each other when encountering difficulties, a process they ...

You can expect three times the transcriptional yield (4 mg/mL) and a much-improved capping efficiency (>95%) over traditional methods. The mRNA cap structure is an important point of consideration for ...

View Full Profile. Learn about our Editorial Policies. During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, ...

This information is first transcribed into messenger RNA (mRNA), which then serves as ... by providing a favorable context for the ribosome to recognize the start codon. Eukaryotic and Prokaryotic ...

According to the terms of the agreement, TriLink will supply its patented CleanCap® M6, CleanCap® AG 3’OMe, CleanCap® AG, and CleanCap® AU cap analogs for use in Aldevron’s mRNA ...