Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small ...

Combined serum CA19-9 and miR-27a-3p in peripheral blood mononuclear cells to diagnose pancreatic cancer. Cancer Prev ... The evaluated study examined the miRNA profiles in peripheral blood ...

Lara Mahal, University of Alberta However, the team soon replicated their findings in four cancer cell lines taken from the lungs, ovaries, pancreas, and colon. Furthermore, mutating potential miRNA ...

Over the past two decades, several methods have been developed to allow comparative studies of gene expression between normal and cancer cells. Starting with simple approaches that used gel ...

The following is a summary of "Epigenetic-modification associated hnRNPA3 acts as a prognostic biomarker and promotes malignant progression of HCC," published in the April 2025 issue of BMC Cancer by ...

Their work, published in Advanced Science ("Targeted DNA Nanomachine Enables Specific miRNA-Responsive Singlet Oxygen Amplification for ... Confocal imaging and qPCR confirmed that microRNA-7 ...

Through the mouse model, the researchers found that a cluster of miRNAs, labeled miRNA 290-295 in mice, were exclusively expressed and secreted by undifferentiated testicular cancer cells.

Malignant testicular germ cell tumors are the most common cancers diagnosed in males ages 15 to 39 in the U.S., though incidence has increased by almost 40% in the last 50 years. At the same time, ...

Moreover, circRNAs primarily operate as competitive endogenous RNAs (ceRNAs), effectively "sponging" miRNAs and thereby ...

Cancer cells utilize specific micro-ribonucleic acids (miRNAs)-small noncoding RNAs to regulate gene expression and promote ... their efforts on nanowire-based miRNA extraction and machine ...