Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a ...

Nave and his colleagues hypothesized that myelin, a protective fatty layer that encloses axons (i.e., nerve fibers) in the ...

Cognito Therapeutics, a neurotechnology company advancing disease-modifying therapies to treat CNS diseases, today announced ...

Damage to myelin, the protective sheath surrounding nerve fibers, impairs the brain's ability to transmit signals efficiently ...

The inability of the CNS to effectively regenerate lesions has ... Alternatively, or in addition to, factors neutralizing the effects of myelin-associated inhibitors may further enhance the ...

Even if these MAP antigens were not homologs of CNS myelin proteins, they share sequence homology with myelin protein P0, T-cell receptor (TCR)-γ chain C region, complement activation product C1q ...

Initial experiments to determine which CNS cell types are most vulnerable ... accompanied by a syndrome of worsening delayed damage to myelin. This 'late' damage was associated with abnormal ...

ultrastructural neuropathology of and adhesive mechanisms in CNS and PNS myelins; remyelination; spinal cord injury. Our current research interests are focused on the structure and dynamic membrane ...

The research report titled: “Selective retinoid X receptor agonism promotes functional recovery and myelin repair in experimental autoimmune encephalomyelitis”, G.D.S Kasheke, et al ...

The CNS includes the brain, spinal cord, and optic nerves. MS involves the immune system damaging myelin — a substance that surrounds and protects nerve fibers. Damaged areas of myelin are ...