Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning ...

For example, cells can digest long-lived proteins to release amino acids. How did this process of self-eating evolve? How is it controlled by the cell? Today, research on autophagy is a growing ...

Beyond a threshold (which is lowered when autophagy is inhibited), such stress causes apoptosis. Several proteins that have an essential role in autophagy have a direct or indirect impact on the ...

Proteasomes are protein complexes that break down faulty proteins into smaller peptides. On the other hand, autophagy is a process by which cells degrade and recycle larger structures, including ...

This essential cleaning process enables them to capture and degrade unnecessary or dysfunctional macromolecules, such as damaged organelles, protein aggregates, and microbial pathogens. As a result, ...

Similarly, autophagy is the body’s first-line of defense against the buildup up of toxic substances, degrading old organelles and proteins to provide new substrates and building blocks. In this way, ...

Autophagy is an essential process in which cells remove their "junk" components - such as damaged proteins, malfunctioning organelles, or harmful pathogens, such as bacteria and viruses ...

This phenomenon, named autophagy, was one that differed in nature compared to prior physiological knowledge. Tens of thousands of different protein types exist within our bodies, and these substances ...

Parkinson’s disease is a brain disorder that affects movement, making everyday tasks difficult for nearly one million people ...

Autophagy loss increases PC vulnerability, independent of its role in protein and mitochondria quality control. Credit: Nature Metabolism (2025). DOI: 10.1038/s42255-024-01196-4 ...

A research team affiliated with UNIST has unveiled an innovative technology to eliminate drug-resistant cancer cells using ...

Autophagy is a degradation process of proteins in cells during a state of nutrient starvation. It is a basic and primary function found in almost all eukaryotes, from yeasts to humans. Since ...