Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning ...

made it possible to analyse mammalian cells that express autophagy proteins tagged with fluorescent markers. Time-lapse studies provide compelling images which suggest that autophagosome formation ...

Beyond a threshold (which is lowered when autophagy is inhibited), such stress causes apoptosis. Several proteins that have an essential role in autophagy have a direct or indirect impact on the ...

A membrane encloses a part of the cytoplasm (autophagosome), which then becomes merged (autolysosome) with an organelle (lysosome) containing various degrading enzymes, causing the contained proteins ...

Autophagy is an essential process in which cells remove their "junk" components - such as damaged proteins, malfunctioning organelles, or harmful pathogens, such as bacteria and viruses ...

Autophagy is a degradation process of proteins in cells during a state of nutrient starvation. It is a basic and primary function found in almost all eukaryotes, from yeasts to humans. Since ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

Just like people declutter their homes to prevent the accumulation of broken or unwanted items, cells use autophagy to maintain homeostasis. This essential cleaning process enables them to capture and ...

Parkinson’s disease is a brain disorder that affects movement, making everyday tasks difficult for nearly one million people ...

Autophagy loss increases PC vulnerability, independent of its role in protein and mitochondria quality control. Credit: Nature Metabolism (2025). DOI: 10.1038/s42255-024-01196-4 ...

We have observed implantation defects and thus, reduced fecundity in conditional knockout mice models of the autophagy-related proteins in the reproductive tract. In the absence of these proteins, we ...

We have observed implantation defects and thus, reduced fecundity in conditional knockout mice models of the autophagy-related proteins in the reproductive tract. In the absence of these proteins, we ...