The pharmacological stimulation of autophagy may have cytoprotective effects, for example, in mouse models of neurodegenerative disease, whereas the inhibition of autophagy can sensitize cancer ...

Every year, neurodegenerative diseases take a steep toll on millions of people, affecting individuals, their caregivers, families and communities. Most neurodegenerative diseases share a common ...

Neurodegenerative diseases pose a serious threat to public health, with an increasing impact among the elderly population.

Josephine Thinwa shares her journey to becoming a physician scientist and how this led her to investigate the role of a neurologically important kinase in virus-induced autophagy. Just like people ...

While this mechanism has so far only been shown in mice, further studies will investigate how autophagy regulates metabolism in both mouse and human-based models of neurodegenerative diseases.

Breakthrough NUS discovery sheds light on cellular recycling mechanism and potential for treating rare diseases Singapore ...

More information: Suhyun Kim et al, Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in ...

Impaired autophagy is linked to cardiovascular diseases, neurodegenerative diseases like Alzheimer's disease and Parkinson's disease, and metabolic disorders like diabetes and cancer. Various ...

Impairment of autophagy precedes both amyloid beta and tau tangles, and therefore anticipates the neurodegenerative process in Alzheimer’s disease NEW YORK, Jan. 15, 2025 (GLOBE NEWSWIRE ...