In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

The process of autophagy is a cell survival mechanism that occurs when the cell is under stress, via external environmental pressures, including the lack of nutrients, or via the internal ...

Get Instant Summarized Text (Gist) Autophagy, particularly through the protein ATG5, plays a crucial role in maintaining brain health by regulating glucose metabolism in neurons. In Purkinje cells ...

This process, known as autophagy, is like a self-cleaning mechanism for cells, helping the cells stay healthy by getting rid of damaged parts and recycling useful components. The process involves ...

Annexin-V is a specific PS-binding protein that can be used to detect apoptotic cells by binding to PS. In general, this is not an early event in autophagy and the the role of PS externalisation is ...