The relationship between autophagy and cell death is complex because autophagy constitutes an adaptive response to different kinds of stress by which the cells avoid cell death; yet, in some ...

复旦大学附属中山医院等多单位的研究人员 Linnan Li、Hao Cheng 等人在《Cell Death Discovery》期刊上发表了题为 “METTL3 regulates autophagy of hypoxia - induced cardiomyocytes by targeting ATG7” 的论文。该研究揭示了 METTL3 ...

Indeed, recent research indicates that there are other forms of programmed cell death, including an intracellular degradation process known as autophagy, which we found SAHA can trigger. Currently, we ...

The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway autophagy, scavenging pathways such as ...

These disruptions ultimately resulted in Purkinje cell death and motor gait dysfunction, underscoring the critical role of autophagy in maintaining cerebellar health. "Our research demonstrates ...

Autophagy, the cell's essential housekeeping ... micronucleophagy due to the lack of normal macronucleophagy causes cell death. This work was led by Ph.D. student Ziyang Li from the Institute ...

Therefore, when cells notice they have too much "junk" inside, autophagy kicks into action. It is like a little clean-up crew inside the cell that sorts out the waste, recycles useful parts ...