Moreover, the conditions required for inducing dendritic-cell maturation by apoptotic cells are still controversial and have been recently the subject of intense investigation ...

The identification of delayed-onset cell death has allowed for the manipulation of cellular responses through the regulation of apoptosis. We hypothesized that in addition to delayed apoptotic ...

"Therefore, its activity and regulation is decisive in whether or not tumor cells respond to a given therapy. When a tumor is resistant to a treatment, the cause may be an increased activity of ...

Therefore, the removal of cells from a tissue, called apoptotic extrusion, occurs regularly. Its balance is key for epithelia homeostasis. In addition to this role in tissue homeostasis ...

The human body is estimated to remove 1% of its body mass, likely more than 200 billion cells, every day. To achieve this, we rely on a highly evolutionarily conserved process: apoptotic cell ...

The European Medicines Agency has recommended three new medicines to treat breast and cervical cancer and chemotherapy-induced neutropenia.

When a tumor is resistant to a treatment, the cause may be an increased activity of anti-apoptotic proteins of this family that block the cell death process." The study methodology successfully ...