Apoptotic DNA degradation has been thought to be a cell-autonomous process. Recent evidence suggests that heterophagic recognition and engulfment of dying cells by non-apoptotic cells may be ...

However, cell retraction appears not to be compulsory for blebbing as expression of cleaved ROCK-I can induce blebbing in non-apoptotic cells 7 and in non-adherent Jurkat cells 6.

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated.

A recent study showed that paracrine delivery of miR-21a-5p by bone marrow mesenchymal stem cells-derived apoptotic bodies ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

"In other words, if one cell dies, so does its sister. In our study, we have shown that the apoptotic pairing is prevented when the bridge is eliminated. It plays a key role." The bridge acts as a ...

Mammalian hosts coordinate various cell death pathways as part of the ... Consequently, the production of pro-apoptotic truncated BID (tBID) is suppressed while the abundance of pro-necroptotic ...