Antigen-presenting cells (APCs) are a heterogeneous group of immune cells that mediate the cellular immune response by processing and presenting antigens for recognition by certain lymphocytes ...

Recent progress in molecular medicine has provided important tools to identify antigen-specific T cells. In most cases, the approach is based on oligomeric combinations of recombinant major ...

Lapuleucel-T (APC8024), an autologous active cellular immunotherapy, was prepared from peripheral-blood mononuclear cells, including antigen-presenting cells, that were activated in vitro with ...

Acellular Artificial Antigen-presenting Cells. Acellular artificial antigen-presenting cells (aAPCs) are micro- or nano-particle-based reductionist systems that mimic the biological cues given by ...

Background: Gammadelta T cells (γδ T cells), a subset of T cells, are involved in protective immunity system through cytokine secretion and cytotoxic activity. Recently, γδ T cells also have been ...

In this article, ACROBiosystems discuss the importance of T cells in the immune response and shares some essential tips and methods for culturing T-cells efficiently and effectively.

Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction ...

Preliminary scientific report. Jennifer Connors, David Joyner, Nathan Mege, et al. Lipid nanoparticles (LNP) induce activation and maturation of antigen-presenting cells in young and aged ...

MHC class II molecules, which are expressed on antigen-presenting cells (APCs) (e.g., B cells, monocytes, and central nervous system [CNS] microglia), are required for the presentation of ...

Although the mRNA COVID-19 vaccines from Pfizer-BioNTech and Moderna are safe and effective at preventing severe illness in adults and children, including immunocompromised individuals ...

But a study published yesterday (September 15) in Nature Cell Biology suggests that an interaction between T cells and antigen presenting cells (APCs) early in the immune response to viruses may ...

Thetis Cells Train the Immune System To Tolerate Helpful Outsiders. Thetis cells are a type of antigen-presenting cell, whose job is to present foreign substances (antigens) to other immune cells.