Many challenges will have to be faced in the next decade to bring more efficient and affordable antibody-based drugs to the clinic. Here, we discuss strategies to select the best therapeutic ...

RubrYc’s lead programs include RTX-002, an anti-PD-1 agonist for serious autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis, and RTX-003, an anti-CD25 antibody that ...

Researchers from Walter and Eliza Hall Institute of Medical Research, The University of Melbourne and affiliated organizations presented the development of a new reporter mouse model designed to study ...

An Australian man credited with saving more than 2 million babies through decades of regular blood and plasma donations has ...

Directed by high IL-12 levels, B cells produce interferon gamma and more IL-12 to create an autocrine positive feedback loop that locks in the extrafollicular response decision. “This IL-12 ...