Polymerized actin forms highly dynamic networks that allow cells to respond to and interact with their environment. This includes the lamellipodia that facilitate cell movement and the so-called ...

UCLA professor of integrative biology and physiology David Walker, PhD, and colleagues, in addition showed that tweaking a few specific genes in aging fruit flies’ neurons prevented this F-actin ...

The new study shows that preventing F-actin accumulation led to much more active autophagy in the brains of aged fruit flies.

In contrast to the well-characterized configurations of actin filaments in NKs during the lytic process, there is a gap of knowledge regarding the organization and role of the tumor cell actin ...

Not only have researchers identified how a common cellular protein affects aging, but they’ve tweaked the genes that produce it in fruit flies, extending healthy lifespan by 25% to 30%. The ...

Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste ...

Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste ...

Vesicle‐Associated Actin Assembly by Formins Promotes TGF β ‐Induced ANGPTL4 Trafficking, Secretion and Cell Invasion. Advanced Science , 2023; 2204896 DOI: 10.1002/advs.202204896 Cite This ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

Humans aren’t the only ones who grow forgetful as they age — fruit flies do, too. But because fruit flies have a lifespan of only about two months, they can be a useful model for understanding the ...