Protein translocation is an essential, nano-scale dynamic process that facilitates the movement of proteins across cellular ...

Kinesins contain a conserved motor domain for ATP hydrolysis and microtubule binding, and divergent non-motor domains for family-specific regulatory mechanisms and functions. The regulation of ...

acts as the motor domain of the molecule and pulls actin filaments along by repetitive conformational changes coupled to ATP hydrolysis. But to understand fully even this fundamental aspect of ...

The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...

In nature, this is achieved by a machinery of proteins: motor proteins powered by chemical energy from ATP hydrolysis pull together a ring of filaments of the protein actin. Adenosine triphosphate ...