该研究揭示了Aβ病理引发的神经元过度活跃和功能连接增强，是促进tau病理扩散的关键机制。 近期，德国慕尼黑大学中风和痴呆症研究所Nicolai ...

Researchers say CSF biomarker test correlates with the severity of cognitive decline, independent of other factors, including brain amyloid deposition.

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering ...

我们知道，β-淀粉样蛋白（Aβ）沉积导致的淀粉样斑块，以及tau蛋白过度磷酸化导致的神经纤维缠结，是阿尔茨海默病（AD）的两个典型病理特征。

引言阿尔茨海默病(Alzheimer’s Disease, AD)的典型神经病理学特征之一,是tau蛋白异常磷酸化形成的神经原纤维缠结(neurofibrillary tangles, ...

Researchers from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) have found that tau protein and beta-amyloid – two pathological hallmarks of Alzheimer’s disease – ...

阿尔茨海默病（Alzheimer's Disease, ...

Researchers found that COVID-19 may accelerate biological processes linked to Alzheimer’s, showing changes in brain-related ...

Enter SynPull, a new synaptosome imaging method developed by David Klenerman, John Danial, and colleagues at the University of Cambridge, England. SynPull combines single-molecule pull-down of ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Feb. 6, 2025 — A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta-amyloid -- affect brain circuits in distinct yet synergistic ways ...