A crystal structure of Ro bound to a misfolded pre-5S rRNA fragment reveals that the tail inserts into the cavity, while a helix binds on the surface. Most contacts of Ro with the helix are to the ...

Preribosomal particles need to be exported from the nucleus, but their architecture and composition have been unknown. Cryo-EM analysis of pre-60S particles bound to the nuclear export factor Arx1 ...

This article describes the production of 18S, 5.8S, 28s, and 5S rRNAs in eukaryotes, and post-translational modifications of tRNA and mRNA.

The ribosomal structure is highly conserved between all species, ... (18S rRNA) and large subunit (5S, 5.8S, and 25S rRNA) alongside the 79 r-proteins (80 in other eukaryotes).

Ribosomal RNA (rRNA) is a type of non-coding RNA that is a crucial component of ribosomes, the cellular machinery responsible for protein synthesis.Non-coding RNA refers to RNA molecules that are not ...

Researchers of the Cancer Metabolism group at the IDIBELL and the University of Cincinnati, led by George Thomas, have discovered a role for ribosomal 5S RNA in the formation of a complex that ...

Researchers of the Cancer Metabolism group at the Bellvitge Biomedical Research Institute (IDIBELL), Catalan Oncology Institute (ICO) and the Division of Hematology-Oncology of the University of ...